AI Article Synopsis
- The acute respiratory distress syndrome (ARDS) lung is small and uneven, and mechanical ventilation can lead to both physical and inflammatory damage.
- The benefits of gentle lung treatment that reduces stress and strain in the lungs have been established.
- There is a need to recognize the significance of lung perfusion and to incorporate measurements like transpulmonary pressure and end-expiratory lung volume into standard mechanical ventilation practices.
Article Abstract
In the last several years, we definitely learned that the acute respiratory distress syndrome lung is small, nonhomogeneous, and that mechanical ventilation in this baby lung may cause physical damage as well as inflammatory reaction. The clinical benefit of the gentle lung treatment, based on a decrease of global/regional stress and strain into the lung, has been finally proved. However, we forgot the importance of lung perfusion and its distribution in this syndrome and, besides a low tidal volume, we still do not know how to handle the other variables of mechanical ventilation. Measurements of variables as transpulmonary pressure and end expiratory lung volume, for a rational setting of mechanical ventilation, should be introduced in routine clinical practice.
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| http://dx.doi.org/10.1097/01.ccx.0000135511.75998.22 | DOI Listing |
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