Purpose. To evaluate the outcome of corneal transplantation and the feasibility of tissue donation from donors with methanol intoxication.Methods. Four corneas from two methanol intoxication victims were procured and transplanted in four patients at our medical center. The outcome and graft survival were evaluated.Results. The recipients were between 12 and 49 years of age. Indications for transplantation were keratoconus (two patients), post-traumatic corneal perforation (one patient) and alkaline burn (one patient). The follow-up period ranged between 12 and 60 months. All grafts remained clear, and the postoperative visual acuity was 20/30 in keratoconus patients and 20/60 in others.Conclusions. The methanol intoxication victims appear to be suitable donors for corneal transplantation. To the best of our knowledge, this is the first study to report successful corneal transplantation from donors with methanol intoxication.
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http://dx.doi.org/10.1023/A:1010180032383 | DOI Listing |
Am J Case Rep
December 2024
Faculty of Medicine, Riga Stradins University, Riga, Latvia.
BACKGROUND Methanol is a toxic alcohol that is often ingested accidentally or intentionally. Its metabolites can induce severe visual disturbances, metabolic acidosis, and neurological dysfunction, which can frequently become life-threatening. CASE REPORT A 44-year-old woman with a history of depression and alcohol use was hospitalized in the Intensive Care Unit after cardiopulmonary reanimation.
View Article and Find Full Text PDFAntiinflamm Antiallergy Agents Med Chem
November 2024
Department of Pharmaceutical Sciences, Dr. APJ Abdul Kalam University, Indore, India.
Objective: This study assessed the In-vitro Antioxidant and In-vivo Analgesics and Anti-inflammatory Activity of Allamanda blanchetii Leaf Extract in Rats.
Introduction: Diverse pharmacological applications of plants from the Apocynaceae family are reported in the literature. Allamanda blanchetii; an ornamental species belonging to the Apocynaceae family, is characterized by diverse biological activities, i.
Eur J Clin Invest
January 2025
Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, Vienna, Austria.
Front Neurol
September 2024
Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
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