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[Seizure prediction: from myth to reality].
Rev Neurol (Paris)
March 2011
Unité d'épileptologie, service de neurologie-1, hôpital de la Pitié-Salpêtrière, AP-HP, and Centre de recherche de l'institut du cerveau et de la moelle épinière, Inserm, UMRS 795, CNRS UMR 7225, UMPC, université Pierre-et-Marie-Curie, 75651 Paris, France.
Introduction: Clinical, metabolic and electrophysiologic studies suggest the existence of a preictal state, a transition between the interictal state and seizure.
State Of The Art: Analysis of the intracranial EEG by mathematical methods shows changes of the brain dynamics several minutes before the occurrence of partial seizures. These modifications can be widespread and not restricted to the epileptogenic focus, which would explain why they can also be detected from scalp EEG.
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