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Vascular hemichorea/hemiballism and topiramate. | LitMetric
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Vascular hemichorea/hemiballism and topiramate.

Emilia Mabel Gatto Claudia Uribe Roca Gabriela Raina Marcelo Gorja Silvia Folgar Federico E Micheli

Mov Disord

Parkinson's Disease and Movement Disorders Program, Department of Neurosciences, Hospital de Clínicas, University of Buenos Aires, Buenos Aires, Argentina.

Published: July 2004

Although vascular hemichorea/hemiballism (HC/HB) has been reported to be self-limited, in some cases, it can be irreversible and severely disabling. The standard treatment includes typical and atypical neuroleptics and GABA-mimetic drugs. Topiramate is a new antiepileptic drug possessing a complex mechanism of action, including the enhancement of GABA-mediated inhibition. We describe a 71-year-old patient with HC/HB who markedly improved after topiramate treatment.

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http://dx.doi.org/10.1002/mds.20086DOI Listing

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