Metronidazol was employed in the endodontic treatment of 200 gangrenous teeth, with symptoms of acute and chronic periodontitis. In 50 cases aerobic and anaerobic microbiological cultivations have been performed. The number of the necessary treatments was less, symptoms of irritation in the periapical region could not be observed. The favourable clinical and microbiological results in the course of the Metronidazol treatment point to the role of the anaerobic microorganisms in connection with the inflammatory symptoms of the gangrenous pulp.
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