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Knockdown of HOXD13 in Oral Squamous Cell Carcinoma Inhibited its Proliferation, Migration, and Influenced Fatty Acid Metabolism.
J Cancer
January 2025
Department of Oral and Maxillofacial Surgery, School of Stomatology, Hebei Medical University, Hebei Technology Innovation Center of Oral Health, Key Laboratory of Stomatology and Clinical Research Centre for Oral Diseases, Hebei Province, Shijiazhuang, 050017, China.
HOXD13, a member of the homeobox gene family, plays a critical role in developmental processes and has been implicated in various malignancies, including pancreatic cancer and glioma. However, its role in oral squamous cell carcinoma (OSCC) remains poorly understood. This study aimed to elucidate the potential of HOXD13 as a diagnostic biomarker and therapeutic target for OSCC.
View Article and Find Full Text PDFRational Fabrication of Functionally-Graded Surfaces for Biological and Biomedical Applications.
Acc Mater Res
December 2024
The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States.
As a ubiquitous feature of the biological world, gradation, in either composition or structure, is essential to many functions and processes. Taking protein gradation as an example, it plays a pivotal role in the development and evolution of human bodies, including stimulation and direction of the outgrowth of peripheral nerves in a developing fetus. It is also critically involved in wound healing by attracting and guiding immune cells to the site of injury or infection.
View Article and Find Full Text PDFClosed trans-intersphincteric fistulotomy: a new modified sphincter-sparing technique for high transsphincteric anal fistula.
Front Surg
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Department of Anorectal Diseases, Shanghai Baoshan District Integrated Traditional Chinese and Western Medicine Hospital, Shanghai, China.
Background: The main goals of surgery for fistula-in-ano are to completely resolve the condition and maintain optimal anal function. Effective management of the internal opening during and proper postoperative drainage of the intersphincter plane are crucial for achieving successful outcomes. This study evaluated the clinical efficacy of a novel sphincter-sparing technique for treating high transsphincteric anal fistula (HTAF).
View Article and Find Full Text PDFResults of treating patients with cellulitis by hyperbaric oxygen: a case-control study.
Int Marit Health
January 2025
Institute of Maritime Medicine, Hai Phong, Vietnam, 21 Vo Nguyen Giap, Le Chan, Kenh Duong, Hai Phong, Vietnam, 18000 Hai Phong, Viet Nam.
Background: Cellulitis is an acute bacterial infection of the skin and subcutaneous tissue. The characteristic symptoms of the disease are an area of skin that is swollen, warmth, redness, pain, unknown borderline, tends to expand, and can lead to tissue necrosis. Hyperbaric Oxygen (HBO) is a non-drug treatment, which has the effect of relieving pain, reducing edema, and accelerating the wound healing process for patients with cellulitis.
View Article and Find Full Text PDFUse of a bioresorbable polylactide sheet (OrthoWrap Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial.
BMC Musculoskelet Disord
January 2025
Orthopedic Department, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Background: Adhesion formation poses a significant challenge for both patients and hand surgeons following tendon repair. One common strategy to prevent adhesion formation is the use of physical barriers. This study aimed to compare the outcomes of extensor tendon repair with and without the application of the OrthoWrap bioresorbable Sheet, specifically in terms of adhesion prevention.
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