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Acrokeratosis paraneoplastica (Basex syndrome) with trachyonychia preceding the diagnosis of squamous cell carcinoma of the lung.
Dermatol Online J
April 2024
Department of Dermatology, Tulane University, New Orleans USA Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo USA.
Acrokeratosis paraneoplastica (Basex syndrome) is a rare paraneoplastic condition hallmarked by psoriasiform lesion development on acral surfaces, most often related to an underlying squamous cell carcinoma. Patients may also present with nail plate changes. Successful management of this condition can be accomplished by treating the underlying malignancy.
View Article and Find Full Text PDFNail disorders to be kept in mind.
Hand Surg Rehabil
April 2024
Dermatology Department, Université Libre de Bruxelles, University Hospital Brugmann - Saint-Pierre - Children Hospital Queen Fabiola, Brussels, Belgium. Electronic address:
Recognizing and diagnosing the most common nail diseases is essential, to be able to guide patients and provide appropriate treatment. However, uncommon nail disorders should not be neglected, in order to avoid inadequate treatment and above all to ensure that no severe underlying disorder, with severe prognosis, is overlooked.
View Article and Find Full Text PDFBazex Syndrome (Acrokeratosis Paraneoplastica): A Narrative Review of Pathogenesis, Clinical Manifestations, and Therapeutic Approaches.
Cureus
September 2023
Surgery, University of Pittsburgh Medical Center, Pittsburgh, USA.
Acrokeratosis paraneoplastica, also known as Bazex syndrome, is a relatively understudied yet clinically important dermatological condition that is inextricably associated with squamous cell carcinoma, predominantly of the upper respiratory and gastrointestinal tracts. Manifesting as unique psoriasis-like cutaneous lesions, Bazex syndrome functions as an early warning signal for underlying malignancies, underscoring the urgent need for its timely diagnosis and intervention. Notwithstanding its clinical relevance, the molecular and cellular mechanisms underpinning its pathogenesis are not fully understood.
View Article and Find Full Text PDFAcrokeratosis paraneoplastica in tonsillar carcinoma.
Eur J Dermatol
February 2023
Department of Dermatology, Addenbrookes Hospital, Cambridge University Trust, UK.
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