Aims: To investigate the presence of the antigliadin antibodies in the patients with Graves' disease and Hashimoto's thyroiditis.
Methodology: Four hundred patients with autoimmune thyroid disease (280 Graves' disease and 120 Hashimoto's thyroiditis ) were included in the study. The patients with celiac sprue patients were excluded. For the diagnosis of autoimmune thyroiditis, blood levels of thyrotropin (TSH), free thyroxine (FT4), and the titration of thyroid autoantibodies (TgAb and TmAb) were measured, and the thyroid gland was ultrasonographycally evaluated. After the diagnosis of autoimmune thyroid disease was established, the titration of antigliadin antibodies (Ig A and B) were routinely detected.
Results: Twenty two patients (5.5 per cent) with autoimmune thyroiditis had positive antigliadin antibodies. Polyglandular endocrine syndrome was diagnosed in most of these patients.
Conclusions: We claim that polyglandular endocrine syndrome is the commonest cause of positivity of antigliadin antibodies in the patients with autoimmune thyroid disease.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Introduction: Primary sclerosing cholangitis (PSC) is a biliary disorder associated with a high risk of end-stage liver disease and cholangiocarcinoma (CCA). Currently prediction of the unfavorable outcomes is hindered by the lack of valuable prognostic biomarkers.
Objectives: The aim of the study was to assess the prevalence of the autoantibodies in PSC and define their potential use as the predictors of progressive disease and CCA in a large, prospective cohort of PSC patients.
Prevalence of celiac disease-specific antibodies and their association with clinical status and environmental factors.
Heliyon
December 2024
Grupo de Investigaciones Básicas y Aplicadas en Inmunología y Bioactivos (GIBAIB), Instituto de Ecología y Desarrollo Sustentable (INEDES), (Universidad Nacional de Luján - CONICET), Luján, Buenos Aires, Argentina.
Background And Aims: Celiac disease (CeD) affects 1-2% of the world's population. The aim of this study was to relate the incidence of CeD-related serological markers to symptoms, pathologies, and environmental exposure to wheat flour, given the number of flour mills present in the region.
Materials & Methods: Serum samples were collected from 537 inhabitants from a rural city.
<b>Background and Objective:</b> Autism Spectrum Disorder (ASD) is a range of neurodevelopmental disabilities that lack a clear etiology. To date, studies investigating the role of immune reactivity to gluten in ASD have been inconsistent. This study aimed to compare levels of gluten reactivity markers in 319 ASD patients to 172 of their unaffected siblings and 322 of unrelated healthy controls (UHC).
View Article and Find Full Text PDFReview of Integrative Medical Therapies for Psoriasis: The Microbiome, Probiotics, Diet, and Mindfulness.
J Psoriasis Psoriatic Arthritis
July 2024
Integrative Skin Science and Research, Sacramento, CA, USA.
Background: Psoriasis is a chronic inflammatory condition with cutaneous and systemic involvement. Although many efficacious treatment options are available, concerns regarding costs and duration of treatment have expanded interest in the role of integrative medical therapies for psoriasis.
Objective: In this review, we aim to provide evidence for the use of integrative medical approaches in the management of psoriasis, namely approaches utilizing the microbiome, probiotics, diet, and mindfulness.
Review article: Faecal biomarkers for assessing small intestinal damage in coeliac disease and environmental enteropathy.
Aliment Pharmacol Ther
October 2024
Department of Pediatric Research, Faculty of Medicine, University of Oslo, Oslo, Norway.
Article Synopsis
- The study investigates the potential of using stool samples as non-invasive biomarkers to evaluate small intestinal damage in conditions like coeliac disease and environmental enteropathy, where traditional biopsy methods are currently used.
- A systematic search led to the inclusion of 35 relevant studies focusing on various faecal markers, such as faecal calprotectin and antibodies related to gluten sensitivity, which showed mixed results in their reliability for assessment.
- The authors conclude that more research is necessary to identify consistent and reliable faecal biomarkers that can accurately reflect small intestinal mucosal damage, particularly in environmental enteropathy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!