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Identification of Two Immunoglobulin Light Chain Types and Expression of Immunoglobulin Diversity in Chinese Giant Salamander (Andrias davidianus).
Dev Comp Immunol
March 2025
College of Animal Science and Technology, Northwest A&F University Shaanxi,China. Electronic address:
Lacking research on immunoglobulins in the Chinese giant salamanders (Andrias davidianus) has left their populations vulnerable to pathogen infections, contributing to a sharp decline in their numbers. In this study, we employed the rapid amplification of cDNA ends (RACE) technique along with paired-end 300 bp read length (PE300) sequencing. This approach was used to construct a DNA library, which enabled us to investigate the diversity of immunoglobulin gene expression.
View Article and Find Full Text PDFSex differences in electrical activity of the brain during sleep: a systematic review of electroencephalographic findings across the human lifespan.
Biomed Eng Online
March 2025
KITE Toronto Rehabilitation Institute, University Health Network, 550 University Avenue 11th Floor, Rm 11-183, Toronto, ON, M5G 2A2, Canada.
Background: With the explosion of techniques for recording electrical brain activity, our recognition of neurodiversity has expanded significantly. Yet, uncertainty exists regarding sex differences in electrical activity during sleep and whether these differences, if any, are associated with social parameters. We synthesised existing evidence applying the PROGRESS-Plus framework, which captures social parameters that may influence brain activity and function.
View Article and Find Full Text PDFRacial and ethnic disparity in obstetric anaesthesia: a systematic review and meta-analysis.
Anaesthesia
March 2025
Department of Anaesthesia and Perioperative Medicine, University College London Hospitals, London, UK.
Introduction: Racial and ethnic disparities in obstetrics persist globally despite improvements in maternal mortality rates and are related to access, experience and outcomes. We aimed to elucidate the racial and ethnic disparity in obstetric analgesia and anaesthesia.
Methods: Databases were searched and we included studies published in the English language conducted in all countries.
Perioperative Risks and Outcomes in Asian American Patients with Type 2 Diabetes Mellitus and/or Metabolic Syndrome: a Systematic Scoping Review.
J Racial Ethn Health Disparities
March 2025
Department of Anesthesiology, University of Miami Miller School of Medicine, 1400 NW 12th Ave Suite 4022, Miami, FL, 33136, USA.
Asian Americans (AA) have an increased risk of developing type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) compared to non-Hispanic White Americans, yet over half of AA patients with T2DM are underdiagnosed or untreated. Surgical stress, known to exacerbate hyperglycemia in T2DM, is also associated with increased morbidity and mortality. Thus, AA patients may be at elevated risk of experiencing poor outcomes following surgery.
View Article and Find Full Text PDFPrevalence and moderators of depression symptoms among black individuals in Western Countries: a systematic review and meta-analysis among 1.3 million people in 421 studies.
Lancet Reg Health Am
April 2025
Interdisciplinary School of Population Health, University of Ottawa, Ottawa, Ontario, Canada.
Background: Black people living in Western countries face a range of structural challenges and disparities (e.g. difficult socio-economic conditions, historical and intergenerational trauma, police brutality, racism) that adversely affect their mental health.
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