In testing paired serum samples from 40 consecutive cases of African tick bite fever, we detected diagnostic antibodies against spotted fever group rickettsiae in 45% of the patients by immunofluorescence assay (IFA) and in 100% of the patients by Western blotting (WB) (P < 0.01). A specific diagnosis of Rickettsia africae infection could be established in 15% of the patients by IFA and in 73% of the patients by a combination of WB and cross-adsorption assays (P < 0.01).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC440600 | PMC |
| http://dx.doi.org/10.1128/CDLI.11.4.786-788.2004 | DOI Listing |
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