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Primary hepatocellular carcinosarcoma: A case series and literature review.
Clin Res Hepatol Gastroenterol
January 2025
Department of Hepatobiliary Surgery, General Hospital, Shijiazhuang, Hebei, PR China.
Article Synopsis
- Hepatocellular carcinosarcoma (HCS) is an uncommon and aggressive liver cancer, and this case series aims to improve understanding of its diagnosis and treatment.
- Four patients with HCS were studied, focusing on their symptoms, imaging characteristics, and the significance of p53 mutations in tumor development.
- The study found that prompt surgical intervention and localized chemotherapy are important for managing HCS, while targeted therapy showed promise but had limitations, highlighting a need for more research in this area.
Unusual synchronous and metachronous association of hematologic neoplasms with gynecologic neoplasms: A case series and literature review.
Int J Gynaecol Obstet
December 2024
Department of Internal Medicine, Division of Hematology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
The aim of the present study was to evaluate the occurrence of synchronous or metachronous hematologic and gynecologic malignancies. The medical database of the pathology department at a tertiary center was searched from 2016 to 2024 for cases involving both hematologic and gynecologic tumors. A literature search using Google Scholar and PubMed was also conducted between May and June 2024.
View Article and Find Full Text PDFDextran-Graft-Polyacrylamide/Zinc Oxide Nanoparticles Inhibit of Cancer Cells in vitro and in vivo.
Int J Nanomedicine
November 2024
Faculty of Chemistry, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine.
Introduction: Tumor drug resistance and systemic toxicity are major challenges of modern anticancer therapy. Nanotechnology makes it possible to create new materials with the required properties for anticancer therapy.
Methods: In this research, Dextran-graft-Polyacrylamide/ZnO nanoparticles were used.
Study on the expression and prognostic relationship of in liver cancer based on bioinformatics.
World J Clin Oncol
September 2024
Department of General Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China.
Article Synopsis
- Primary liver cancer is a major health issue with a poor prognosis and high recurrence rates, making early detection vital yet difficult.
- Myosin proteins, especially a specific myosin light chain, are key in the development of cancer and may serve as biomarkers for prognosis, particularly in liver hepatocellular carcinoma (LIHC).
- The study found that this myosin light chain is highly expressed in LIHC and correlates with worse overall and disease-free survival, indicating its potential as a target for further research and treatment strategies.
Spontaneous rupture as the initial symptom of primary hepatic carcinosarcoma: A case report.
Asian J Surg
August 2024
Department of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, China. Electronic address:
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