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The global prevalence of interstitial lung disease in patients with rheumatoid arthritis: a systematic review and meta-analysis.
Rheumatol Int
January 2025
School of Medicine, The University of Western Australia, 35 Stirling Highway, Perth, WA, 6009, Australia.
This study aims to review the literature and estimate the global pooled prevalence of interstitial lung disease among patients with rheumatoid arthritis (RA-ILD). The influence of risk factors like geography, socioeconomic status, smoking and DMARD use will be explored. A systematic review was performed according to the PRISMA and JBI guidelines.
View Article and Find Full Text PDFClinical research framework proposal for ketogenic metabolic therapy in glioblastoma.
BMC Med
December 2024
Biology Department, Boston College, Chestnut Hill, MA, 02467, USA.
Article Synopsis
- Glioblastoma (GBM) is the deadliest brain tumor in adults, and current therapies are largely ineffective, which drives the need for new treatment strategies based on the tumor's metabolic needs, specifically glucose and glutamine.
- A ketogenic metabolic therapy (KMT) approach targets these metabolic pathways by combining dietary changes with specific drugs to limit glycolysis and glutaminolysis, while promoting the use of non-fermentable fuels like ketones and fatty acids.
- The glucose-ketone index (GKI) serves as a biomarker to monitor treatment effectiveness, aiming to create a more hostile environment for tumor growth and improve outcomes in GBM as well as potentially other cancer types reliant on similar metabolic pathways.
Recent trends in representation of female radiologists in radiology annual scientific meetings.
Curr Probl Diagn Radiol
November 2024
Massachusetts General Hospital, Boston, MA, USA, 02114; Harvard Medical School, Boston, MA, USA, 02138.
Article Synopsis
- The study aimed to assess how well women were represented as speakers at U.S. radiology annual scientific meetings from 2019 to 2022.
- At the Society of Interventional Radiology (SIR), female speaker representation rose from 20.0% to 26.5%, while the American Roentgen Ray Society (ARRS) saw fluctuations, peaking at 48.5% in 2022 after dropping in previous years.
- The findings highlight a general improvement in female speaker representation, but emphasize the need for ongoing advocacy and strategies to maintain and promote gender equality in radiology.
Conference Report: Review of Clinical Implementation of Advanced Quantitative Imaging Techniques for Personalized Radiotherapy.
Tomography
November 2024
Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA 19104, USA.
The topic of quantitative imaging in radiation therapy was presented as a "Masterclass" at the 2023 annual meeting of the American Society of Radiation Oncology (ASTRO). Dual-energy computed tomography (CT) and single-positron computed tomography were reviewed in detail as the first portion of the meeting session, with data showing utility in many aspects of radiation oncology including treatment planning and dose response. Positron emission tomography/CT scans evaluating the functional volume of lung tissue so as to provide optimal avoidance of healthy lungs were presented second.
View Article and Find Full Text PDFChinese expert consensus on the management of hypertension in adults with type 2 diabetes.
J Evid Based Med
December 2024
Department of Hypertension and Endocrinology, Army Medical University, Chongqing, China.
Article Synopsis
- Hypertension and type 2 diabetes contribute to an increased risk of premature death and related diseases, particularly affecting the same population.
- An expert consensus using the GRADE approach was formed to create strategies aimed at reducing cardiovascular and kidney-related deaths while minimizing treatment burdens for adults with type 2 diabetes.
- A multidisciplinary team developed 12 evidence-based recommendations focusing on screening, monitoring, lifestyle changes, and medication for individuals with type 2 diabetes, specifically addressing those who also have hypertension.
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