The authors provide the results of the treatment and prophylaxis of peptic ulcer (PU) patients followed up by the polyclinic for 14 years. On a large factual material they estimate the efficacy of PU patients treatment with the use of drugs belonging to different groups, including drugs that exert antisecretory, cytoprotective and antibacterial effects. During the follow-up period, the number of patients with medium-grave and grave PU decreased whereas that of patients with mild disease and no relapses rose for 4-5 years and over (from 4.8% in 1972 to 39.6% in 1989). It has been established that the efficacy of rehabilitation measures for PU is determined by a lot of factors, first of all by adequate drug therapy with the use of the novel pharmacological preparations: selective blockers of histamine H2-receptors (ranitidine, famotidine), colloidal bismuth subcitrate (de-nol) that exert a cytoprotective and antibacterial action on Helicobacter pylori. The combination of the indicated remedies with antibacterial drugs (trichopol, oxacillin, furazolidon) for the treatment of PU relapses and their prevention is based.
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J Neurol
January 2025
Turner Institute for Brain and Mental Health, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, 18 Innovation Walk, Clayton, Victoria, 3800, Australia.
Background: Huntington's disease (HD) is a rare neurodegenerative disease that causes progressive cognitive, physical, and psychiatric symptoms. Computerised cognitive training (CCT) is a novel intervention that aims to improve and maintain cognitive functions through repeated practice. The effects of CCT have yet to be established in HD.
View Article and Find Full Text PDFInt Orthop
November 2024
Department of Orthopedics the First College of Clinical Medical Sciences, China Three Gorges University & Yichang Central People's Hospital, Yichang, 443002, China.
Purpose: To compare the efficacy of an internal brace and the arthroscopic Broström-Gould procedure for chronic lateral ankle instability (CLAI).
Methods: The clinical data of 71 patients who were diagnosed with chronic lateral ankle instability between May 2020 and May 2022 were retrospectively analyzed. The American Orthopedic Foot and Ankle Society (AOFAS) scale, Foot and Ankle Ability Measure (FAAM), and Visual Analogue Scale (VAS) were used to assess clinical outcomes.
JACC Heart Fail
January 2025
Department of Cardiovascular Medicine, Kitasato University School of Medicine, Kanagawa, Japan.
Background: Acute decompensated heart failure (ADHF) leads to hospitalizations and functional decline in older adults. Although cardiac rehabilitation (CR) is effective for stable heart failure, its impact on ADHF patients, particularly those without frailty, is unclear.
Objectives: The goal of this study was to evaluate the efficacy and safety of early in-hospital CR for patients hospitalized with ADHF who are not frail.
J Funct Morphol Kinesiol
December 2024
Department of Physical and Mental Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80100 Naples, Italy.
Background: This observational study investigates the efficacy of combining local muscle vibration (LMV) therapy and kinesiotaping using the McConnell method (KMcCM) in patients with patellofemoral pain syndrome (PFPS). PFPS is a prevalent knee condition characterized by anterior or medial knee pain exacerbated by activities that overload the patellofemoral joint.
Objective: The primary aim of this study was to evaluate the effectiveness of LMV combined with KMcCM in reducing pain and improving function in PFPS patients.
Front Psychol
January 2025
Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Objective: To systematically investigate the effect of Internet-based cognitive-behavioral therapy (ICBT) on depression, anxiety, fatigue and quality of life (QOL) in patients with breast cancer (BC).
Methods: A systematic review with meta-analysis and qualitative evidence synthesis was performed. Ten databases, including PubMed, Web of Science, EMBASE, the Cochrane Library, CINAHL, JBI Chinese Biomedical database (CBM), China National Knowledge Infrastructure (CNKI), VIP, and Wanfang, were searched from the start till August 2023.
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