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A microenvironment-adaptive GelMA-ODex@RRHD hydrogel for responsive release of HS in promoted chronic diabetic wound repair.
Regen Biomater
November 2024
Institute of Burn Research, Southwest Hospital, State Key Lab of Trauma and Chemical Poisoning, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Chronic diabetic wounds present significant treatment challenges due to their complex microenvironment, often leading to suboptimal healing outcomes. Hydrogen sulfide (HS), a crucial gaseous signaling molecule, has shown great potential in modulating inflammation, oxidative stress and extracellular matrix remodeling, which are essential for effective wound healing. However, conventional HS delivery systems lack the adaptability required to meet the dynamic demands of different healing stages, thereby limiting their therapeutic efficacy.
View Article and Find Full Text PDFSodium Thiosulfate: An Innovative Multi-Target Repurposed Treatment Strategy for Late-Onset Alzheimer's Disease.
Pharmaceuticals (Basel)
December 2024
Department of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Late-onset Alzheimer's disease (LOAD) is a chronic, multifactorial, and progressive neurodegenerative disease that associates with aging and is highly prevalent in our older population (≥65 years of age). This hypothesis generating this narrative review will examine the important role for the use of sodium thiosulfate (STS) as a possible multi-targeting treatment option for LOAD. Sulfur is widely available in our environment and is responsible for forming organosulfur compounds that are known to be associated with a wide range of biological activities in the brain.
View Article and Find Full Text PDFA Bioinspired Antifouling Coating Based on "Host-Guest Interaction" Strategy: Durable Slipperiness and Tunable Transparency.
Small
January 2025
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310058, China.
Article Synopsis
- Lubricant-mediated surfaces face challenges like lubricant loss and poor clarity for antifouling purposes.
- Inspired by globefish skin, slippery Liquid-Like Surfaces (LLSs) use cyclodextrin-eugenol complexes and flexible silicone chains to effectively kill attached organisms and prevent fouling.
- LLSs show excellent antifouling and mechanical properties while maintaining transparency in various water environments, lasting up to 90 days on coated lenses in seawater.
Research Progress and Perspectives on Anti-Poisoning Hydrogen Oxidation Reaction Electrocatalysts for Hydrogen Fuel Cells.
Small
January 2025
National Innovation Platform (Center) for Industry-Education Integration of Energy Storage Technology, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
As global demand for clean and sustainable energy continues to rise, fuel cell technology has seen rapid advancement. However, the presence of trace impurities like carbon monoxide (CO) and hydrogen sulfide (H₂S) in hydrogen fuel can significantly deactivate the anode by blocking its active sites, leading to reduced performance. Developing electrocatalysts that are resistant to CO and H₂S poisoning has therefore become a critical priority.
View Article and Find Full Text PDFEfficacy of Salicylic acid (SA) in Modulating the Dynamics of Pesticide-Thiamethoxam-induced Stress responses in Brassica juncea L. Insights from Biochemical and Molecular Dissection.
Environ Pollut
December 2024
Department of Botany, GDC-Pulwama-192301, Jammu and Kashmir, India. Electronic address:
The present study uncovers the impacts of pesticide-thiamethoxam (TMX- 750 mg L) and salicylic acid (SA- 0.01, 0.1 and 1 mM) in Brassica juncea L.
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