AI Article Synopsis
- The white-coat effect, where hypertensive patients have higher blood pressure readings in a medical setting, lacks an effective office test for detection.
- A study involving 83 adults with uncontrolled hypertension assessed a deep-breath maneuver as a potential diagnostic tool, revealing a 62% prevalence of the white-coat effect among participants.
- The deep-breath test significantly lowered systolic blood pressure readings, suggesting it could help identify the white-coat effect, reduce overtreatment, and limit unnecessary tests without major risks.
Article Abstract
Background: The white-coat effect is a common phenomenon in hypertensive patients, and there is no current useful office test to detect it.
Methods: This was a cross-sectional study. We evaluated the deep-breath maneuver at the office as a diagnostic test of the white-coat effect. Participants included 83 adult patients with uncontrolled office hypertension. We measured sensitivity, specificity, likelihood ratios of different cutoff points, area under receiver operating characteristic (ROC) curve, and 95% confidence intervals. The reference standard used was 24-hour ambulatory blood pressure monitoring.
Results: We included 73 patients [mean age, 58.7 +/- 9.5 years (mean +/- SD); 55% women]. The prevalence of white-coat effect was 62%. Comparing patients with white-coat effect versus those without, the deep-breath test resulted in a mean systolic blood pressure decrease of 17.8 and 10.9 mm Hg (P <.001) and a mean diastolic decrease of 6.6 and 5.4 mm Hg, respectively (P = not significant). The area under the ROC curve of systolic blood pressure change was 0.69 (95% confidence interval, 0.57 to 0.81). Interobserver agreement was very good.
Conclusions: The deep-breath test can be a helpful maneuver for the detection of white-coat effect. It has no major adverse effects and it may help avoid overtreatment and unnecessary further testing procedures.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3122/jabfm.17.3.184 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Non-traditional pulmonary function tests in risk stratification of anatomic lung resection: a retrospective review.
Ther Adv Respir Dis
December 2024
Division of Thoracic and Esophageal Surgery, Department of Surgery, University Hospitals Cleveland Medical Center and Case Western Reserve School of Medicine, Cleveland, OH, USA.
Background: Guidelines advocate pulmonary function testing (PFT) in preoperative evaluation before lung resection. Although forced expiratory volume in 1 s (FEV1) and diffusing capacity of the lungs for carbon monoxide (DLCO) are recommended, they are often poor predictors of complications.
Objectives: Determine if PFT testing results other than FEV1 and DLCO are associated with post-operative complications.
Comparison of the efficacy of two preoxygenation techniques using oxygen reserve index.
Adv Clin Exp Med
September 2024
Department of Anesthesiology and Reanimation, Istanbul Education and Training Hospital (SUAM), University of Health Sciences, Turkey.
Background: Preoxygenation is very important to protect the patient from hypoxia before intubation. However, pulse oximetry has some limitations in detecting hypoxia.
Objectives: We aimed to compare the effectiveness of 2 preoxygenation techniques based on oxygen reserve index (ORI) levels.
Comparing physiological impacts of positive pressure ventilation versus self-breathing via a versatile cardiopulmonary model incorporating a novel alveoli opening mechanism.
Comput Biol Med
September 2024
Department of Mechanical Engineering, University College London, London, WC1E 7JE, UK. Electronic address:
Mathematical models can be used to generate high-fidelity simulations of the cardiopulmonary system. Such models, when applied to real patients, can provide valuable insights into underlying physiological processes that are hard for clinicians to observe directly. In this work, we propose a novel modelling strategy capable of generating scenario-specific cardiopulmonary simulations to replicate the vital physiological signals clinicians use to determine the state of a patient.
View Article and Find Full Text PDFGenetic Factors Associated with the Development of Neuropathy in Type 2 Diabetes.
Int J Mol Sci
February 2024
Department of Internal Medicine and Oncology, Semmelweis University, 1083 Budapest, Hungary.
Neuropathy is a serious and frequent complication of type 2 diabetes (T2DM). This study was carried out to search for genetic factors associated with the development of diabetic neuropathy by whole exome sequencing. For this study, 24 patients with long-term type 2 diabetes with neuropathy and 24 without underwent detailed neurological assessment and whole exome sequencing.
View Article and Find Full Text PDFLack of association between behavioral development and simplified topographical markers of the sleep EEG in infancy.
Neurobiol Sleep Circadian Rhythms
November 2023
University of Fribourg, Department of Psychology, Fribourg, Switzerland.
The sleep EEG mirrors neuronal connectivity, especially during development when the brain undergoes substantial rewiring. As children grow, the slow-wave activity (SWA; 0.75-4.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!