AI Article Synopsis
- Researchers developed a series of benzoxathiin SERAMs, which are compounds with unique chemical structures.
- They introduced different heteroatom-substituted amine side chains to these compounds.
- Small changes to the side chains notably impacted the biological activity, particularly in uterine tissue.
Article Abstract
A series of benzoxathiin SERAMs with heteroatom-substituted amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue.
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| http://dx.doi.org/10.1016/j.bmcl.2004.05.073 | DOI Listing |
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Merck Research Laboratories, Medicinal Chemistry, RY800-B116, PO Box 2000, Rahway, NJ 07065, USA.
Article Synopsis
- Researchers developed a series of benzoxathiin SERAMs, which are compounds with unique chemical structures.
- They introduced different heteroatom-substituted amine side chains to these compounds.
- Small changes to the side chains notably impacted the biological activity, particularly in uterine tissue.
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