Objective: To study the clinical manifestation, diagnosis and treatment of laryngeal neuroendocrine neoplasms.
Method: Three cases of laryngeal neuroendocrine neoplasms were analyzed, of which two cases were diagnosed as atypical carcinoids with radical surgery and neck dissection, another case was diagnosed as asparaganglioma through local neoplastic removal.
Result: Two patients of atypical carcinoids are in a good condition after following up one year and another patient of asparaganglioma is with good prognosis after following up eleven years.
Conclusion: Laryngeal neuroendocrine neoplasms are composed of a morphologically heterogeneous group of lesions. Accurate diagnosis is primarily based on clinical characteristic, microscopic and immunohistochemical examination. In some instances, it may be supported by ultrastructural studies. Difference treatment should be provided to different classified tumor.
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