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Association between dried fruit intake and kidney function: research from univariate and multivariate Mendelian randomized studies.
Front Nutr
October 2024
Department of Nephropathy, The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Article Synopsis
- - The study aimed to determine if there is a causal link between dried fruit intake and kidney function, addressing limitations from previous observational studies that could lead to misleading results.
- - Utilizing a two-sample Mendelian randomization method, the researchers analyzed data to evaluate the effects of dried fruit on kidney function markers like blood urea nitrogen, creatinine, uric acid, and cystatin C, finding a negative association between higher dried fruit intake and poorer kidney function.
- - Although the initial findings suggested a positive effect of dried fruits on kidney function, factoring in alcohol consumption and smoking weakened the causal relationship for uric acid and cystatin C, while completely nullifying it for blood urea nitrogen and creatinine.
Association Between Neck Circumference and Microalbuminuria in Community Residents.
Diabetes Metab Syndr Obes
May 2021
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, 200233, People's Republic of China.
Objective: Neck circumference (NC) represents the subcutaneous fat deposition in the neck and is an effective indicator for evaluating metabolic disorders, such as metabolic syndrome, subclinical atherosclerosis, and non-alcoholic fatty liver disease. Microalbuminuria (MAU) is regarded as a potential sign of systemic endothelial dysfunction and microvascular abnormalities. The aim of this study was to elucidate the association of NC with urine albumin-to-creatinine ratio (UACR) and MAU.
View Article and Find Full Text PDFSoluble receptor for AGE in diabetic nephropathy and its progression in Finnish individuals with type 1 diabetes.
Diabetologia
July 2019
Folkhälsan Research Center, Biomedicum Helsinki, University of Helsinki, Haartmaninkatu 8, 00014, Helsinki, Finland.
Aims/hypothesis: Activation of the receptor for AGE (RAGE) has been shown to be associated with diabetic nephropathy. The soluble isoform of RAGE (sRAGE) is considered to function as a decoy receptor for RAGE ligands and thereby protects against diabetic complications. A possible association between sRAGE and diabetic nephropathy is still, however, controversial and a more comprehensive analysis of sRAGE with respect to diabetic nephropathy in type 1 diabetes is therefore warranted.
View Article and Find Full Text PDFTemporary kidney dysfunction: supplementation with Meriva® in initial, transient kidney micro-macro albuminuria.
Panminerva Med
December 2019
Department of Medical and Oral Sciences and Biotechnology, Irvine3 Labs, University of Chieti-Pescara, Pescara, Italy.
Background: The aim of this registry was to evaluate the efficacy of Meriva® in subjects with temporary kidney dysfunction (TKD) and increased oxidative stress levels. TKD was a casual finding on urinary tests after reported side effects following drug consumption, a clinical event or dehydration.
Methods: Patients followed either standard management (SM) or SM plus Meriva® (Curcumin Phytosome®) supplementation (3 capsules/day, corresponding to 1.
Metabolic Syndrome After Preeclamptic Pregnancy: A Longitudinal Cohort Study.
J Womens Health (Larchmt)
March 2019
3 Maastricht University Medical Centre, Maastricht, The Netherlands .
Introduction: History of preeclampsia increases the risk of cardiovascular disease in women. Most formerly, preeclamptic women have generally one or even more traditional cardiovascular and/or cardiometabolic risk factors consistent with metabolic syndrome in the first year after delivery. The objective of this study was to analyze the prevalence and persistence of risk factors contributing to metabolic syndrome for the course of years after preeclamptic pregnancy.
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