Resorbable polymer implants have become a compelling option in the treatment of acquired and congenital craniofacial deformities. The resorbable polylactide (PLa) and polyglycolide (PGa) polymers in particular have demonstrated excellent safety profile sin multiple in vitro, animal, and clinical studies and are currently being used in a wide variety of craniofacial applications. In this article, the authors discuss the biomaterial properties of PLa and PGa resorbable implants and provide an overview of the use of these polymers in craniofacial surgery. They conclude by relating their experience with an ongoing clinical series using MacroPore PLDLa and FRP implants for various applications,including Le Fort osteotomies, midface/monobloc internal distraction, and craniosynostosis reconstruction.
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http://dx.doi.org/10.1016/j.cps.2004.03.003 | DOI Listing |
J Med Case Rep
January 2025
Department of Pain, The Third Xiangya Hospital and Institute of Pain Medicine, Central South University, Changsha, China.
Background: Interventional therapy of trigeminal neuropathic pain has been well documented; however, intraoperative monitoring and management of pain hypersensitivity remains barely reported, which may pose a great challenge for pain physicians as well as anesthesiologists.
Case Presentation: A 77-year-old Han Chinese male, who suffered from severe craniofacial postherpetic neuralgia, underwent pulsed radiofrequency of trigeminal ganglion in the authors' department twice. The authors successfully placed a radiofrequency needle through the foramen ovale during the first procedure with local anesthesia and intravenous sedation (dexmedetomidine).
Eur Arch Otorhinolaryngol
January 2025
Department of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, University of KwaZulu- Natal, Durban, South Africa.
Purpose: To explore available literature on PNS mucoceles and its distortions of craniofacial-orbital anatomy with regard to orbital bony defects and ophthalmic manifestations, highlighting the PNS mucoceles that mostly result in these distortions.
Methods: A comprehensive literature search was conducted in June 2024 for available literature on the subject matter viz.; Google Scholar, PubMed and Medline, and Cochrane Library.
Nat Commun
January 2025
Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bacterial artificial chromosome transgenic models, including most Cre-recombinases, enable potent interrogation of gene function in vivo but require rigorous validation as limitations emerge. Due to its high relevance to metabolic studies, we perform comprehensive analysis of the Ucp1-Cre line which is widely used for brown fat research. Hemizygotes exhibit major brown and white fat transcriptomic dysregulation, indicating potential altered tissue function.
View Article and Find Full Text PDFAsian J Transfus Sci
September 2022
Department of Paediatric Neurosurgery and Craniofacial Surgery, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham University, Kochi, Kerala, India.
We report the case of a 5-year-old girl with a rare P-null phenotype who presented for a neurosurgical procedure at our center. The case is unique as this patient was one of the two P-null phenotype cases reported in India and we report how we could successfully arrange a rare blood unit for her. As it was challenging to find a donor for her, autologous blood was collected.
View Article and Find Full Text PDFAesthetic Plast Surg
January 2025
Department of Plastic Surgery, The Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing, 210029, Jiangsu Province, China.
Background: Mandibular angle osteotomy (MAO) is a popular procedure to improve facial aesthetics, however, over-resection of the mandibular angle can lead to both functional and aesthetic challenges. Precision is essential in restoring these over-resected mandibles to achieve balanced outcomes. Polyetheretherketone (PEEK) implants offer biocompatibility, durability, and customization potential, making them valuable for achieving precise and predictable results.
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