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Endoscopic treatment of vesicoureteric reflux in paediatric patient: results of a long-term study.
Acta Biomed
August 2011
Unit of Paediatric Surgery, University Hospital of Parma, Parma, Italy.
Background And Aim Of The Work: Vesicoureteric reflux is the most common uropathy in paediatric age. It may be treated with open surgery, antibiotic therapy or endoscopic injection. The purpose of this work is to determine outcomes and experiences of parents with children who underwent endoscopic treatment for VUR.
View Article and Find Full Text PDFWe, the directors of the 27 NIH institutes and centers, wanted to respond to the points made by Andrew Marks in his recent editorial. While we appreciate that the scientific community has concerns, the current initiatives and directions of the NIH have been developed through planning processes that reflect openness and continued constituency input, all aimed at assessing scientific opportunities and addressing public health needs.
View Article and Find Full Text PDFDr. Antonio Scarpa is director of the Center for Scientific Review (CSR) at the National Institutes of Health (NIH). He joined the CSR in July 2005 after 19 years at Case Western Reserve University in Cleveland, Ohio.
View Article and Find Full Text PDFDeterminants of salt sensitivity in black and white normotensive and hypertensive women.
Hypertension
December 2003
Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, Louis Stokes Cleveland VAMC, 11100 Euclid Ave, RB&C 7311, Cleveland, OH 44106-5041, USA.
Salt sensitivity (SS) has been linked to human hypertension. We examined ethnic differences in the relation between SS; erythrocyte sodium (Na+i), calcium (Ca2+i), potassium (K+i), and magnesium (Mg2+i); and sodium pump activity in African-American (AA) and white women. In a crossover protocol, similar numbers of normotensive, hypertensive, AA, and white women were randomized to 7 days of a 20 meq/d and a >200 meq/d salt diet (n=199).
View Article and Find Full Text PDFHormone-stimulated Mg(2+) accumulation into rat hepatocytes: a pathway for rapid Mg(2+) and Ca(2+) redistribution.
Arch Biochem Biophys
May 2002
School of Medicine, Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA.
Many diseases such as cardiac arrhythmia, diabetes, and chronic alcoholism are associated with a marked decrease of plasma and parenchymal Mg(2+), and Mg(2+) administration is routinely used therapeutically. This study uses isolated rat hepatocytes to ascertain if and under which conditions increases in extracellular Mg(2+) result in an increase in intracellular Mg(2+). In the absence of stimulation, changing extracellular Mg(2+) had no effect on total cellular Mg(2+) content.
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