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Transcriptome dynamics in the Arabidopsis male germline during pollen-pistil interactions.
Plant J
March 2025
Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA), Av. da República, Oeiras, 2780-157, Portugal.
When pollen lands on a receptive stigma, it germinates and extends a tube inside the transmitting tissue of the pistil to deliver the sperm cells for double fertilization. The growth of the pollen tube triggers significant alterations in its gene expression. The extent to which these changes occur in the vegetative cell or extend to the sperm cells transported by the tube is unclear but important to determine since sperm cells are believed to acquire a competency for fertilization during pollen-pistil interactions.
View Article and Find Full Text PDFLeveraging artificial intelligence for inclusive maternity care: Enhancing access for mothers with disabilities in Africa.
Womens Health (Lond)
March 2025
Department of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.
Women with disabilities face significant barriers in accessing maternal healthcare, which increases their risk of adverse pregnancy outcomes, particularly in Africa, where resources are limited. Artificial intelligence (AI) presents a unique opportunity to improve inclusivity and accessibility to antenatal care, skilled birth attendance and postnatal care for these women. This paper explores the potential of AI to address the socio-economic, physical, and institutional barriers that limit the utilisation of maternal healthcare services by women with disabilities.
View Article and Find Full Text PDFFactors associated with undernutrition among pregnant women in Chiro district, eastern Ethiopia.
Womens Health (Lond)
March 2025
Department of Biology, College of Natural and Computational Science, Oda Bultum University, Chiro, Ethiopia.
Background: Undernutrition denotes inadequate intake of energy and nutrients to meet one's optimal needs. Pregnant women are at an increased risk of undernutrition due to the added nutritional demand for fetal growth and development. Updated evidence is important for monitoring progress and informing healthcare decisions.
View Article and Find Full Text PDFGDC: Integration of Multi-Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss.
Adv Sci (Weinh)
March 2025
Department of Oto-Rhino-Laryngology, West China Hospital of Sichuan University, Chengdu, 610000, China.
Effective research and clinical application in audiology and hearing loss (HL) require the integration of diverse data, yet the absence of a dedicated database impedes understanding and insight extraction in HL. To address this, the Genetic Deafness Commons (GDC) is developed by consolidating extensive genetic and genomic data from 51 public databases and the Chinese Deafness Genetics Consortium. This repository comprises 5 983 613 variants across 201 HL genes, revealing the genetic landscape of HL and identifying six novel mutational hotspots within the DNA-binding domains of transcription factors.
View Article and Find Full Text PDFRevisiting the Implementation and Effectiveness of Age-Friendly Neighborhood Initiatives in Hong Kong: A Strengths-Based Perspective.
J Aging Soc Policy
March 2025
Shenzhen Tourism College, Jinan University, Shenzhen, Guangdong, China.
In an era where urban environments increasingly grapple with the challenges of an aging population, the necessity for age-friendly neighborhoods (AFNs) has never been more acute. This study investigates the implementation and effectiveness of AFN initiatives in Hong Kong, examining the alignment between policy intentions and their actual impact on the ground. Utilizing a strengths-based perspective, documentary and thematic analysis for gray literature, semi-structured interviews, and focus groups are employed to bridge existing research gaps by highlighting the subjective agency of older adults.
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