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Comparison of Muscle Growth and Dynamic Strength Adaptations Induced by Unilateral and Bilateral Resistance Training: A Systematic Review and Meta-analysis.
Sports Med
January 2025
Metabolism, Nutrition and Exercise Laboratory, Physical Education and Sport Center, State University of Londrina, Londrina, Paraná, Brazil.
Background: Currently, great debate exists over the proposed superiority of some resistance exercises to induce muscular adaptations. For example, some argue that unilateral exercise (meaning one limb at a time) is superior to bilateral exercises (meaning both limbs). Of note, an evidence-based answer to this question is yet to be determined, particularly regarding muscle hypertrophy.
View Article and Find Full Text PDFDebate on the Morphological Variability of the Lateral Pterygoid Muscle-Discrepancies, Speculations and New Original Anatomical Samples.
Medicina (Kaunas)
November 2024
Department of Anatomy, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy, 300041 Timişoara, Romania.
The lateral pterygoid muscle (LPM), a critical component of the masticatory muscles, typically comprises upper (SLPM) and lower (ILPM) heads. However, it is essential to note that the LPM's structure is not a constant feature, as the number of bundles and their topography can vary. Moreover, additional heads, such as medial and middle heads, and unique-headed configurations of the LPM have been reported.
View Article and Find Full Text PDFRetraction Note: MiR-338-5p ameliorates pathological cardiac hypertrophy by targeting CAMKIIδ.
Arch Pharm Res
January 2025
Department of Ultrasound, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong, PR China.
SerpinB1 targeting safeguards against pathological cardiac hypertrophy and remodelling by suppressing cardiomyocyte pyroptosis and inflammation initiation.
Cardiovasc Res
December 2024
Department of Cardiology, The General Hospital of Western Theater Command, No. 270, Tianhui Road, Jinniu District, Chengdu , Sichuan 610083, P.R. China.
Aims: While the pivotal role of inflammation in pathological cardiac hypertrophy and remodelling is widely acknowledged, the mechanisms triggering inflammation initiation remain largely obscure. This study aims to elucidate the role and mechanism of serpin family B member 1 (SerpinB1) in pro-inflammatory cardiomyocyte pyroptosis, heart inflammation, and cardiac remodelling.
Methods And Results: C57BL/6J wild-type, inducible cardiac-specific SerpinB1 overexpression or knockout mice underwent transverse aortic constriction (TAC) surgery.
Eccentric hypertrophy impairs outcome after TAVR.
Clin Res Cardiol
December 2024
Klinik Und Poliklinik Für Innere Medizin I, University Hospital Rechts Der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Article Synopsis
- Aortic stenosis (AS) leads to different patterns of left ventricular (LV) hypertrophy in patients, impacting their clinical outcomes after undergoing transcatheter aortic valve replacement (TAVR).
- A study involving 1,703 patients categorized them based on their LV mass and wall thickness, revealing that those with eccentric hypertrophy (EH) experienced significantly higher mortality rates within one and five years post-procedure compared to other groups.
- Additionally, genetic factors measured by polygenic risk scores (PRS) may help predict the development of hypertrophy patterns and could provide insights into future treatment options for patients with AS.
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