The ability of four 9,10-dihydroethanoanthracene derivatives (BG920, BG932, BG958, and BG996), as well as verapamil and promethazine, to reverse chloroquine resistance was assessed against 24 chloroquine-resistant and 10 chloroquine-susceptible strains of Plasmodium falciparum from different countries. The 9,10-dihydroethanoanthracene derivatives clearly increase chloroquine susceptibility only in chloroquine-resistant isolates.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC434228 | PMC |
| http://dx.doi.org/10.1128/AAC.48.7.2753-2756.2004 | DOI Listing |
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