We evaluated the effect of the combination of micafungin and polymorphonuclear leukocytes (PMN) against hyphae of Candida albicans and Candida dubliniensis. Micafungin enhanced the PMN oxidative burst dose dependently. The combination was synergistic (C. albicans) or additive (C. dubliniensis); when PMN were pretreated with granulocyte-macrophage colony-stimulating factor, the combination was more effective.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC434213 | PMC |
| http://dx.doi.org/10.1128/AAC.48.7.2730-2732.2004 | DOI Listing |
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