Based on preexisting anatomic studies and our experience related to the upper extremity flaps, a proximally pedicled anterior interosseous flap was developed and used in 1 patient for the reconstruction of skin defect of cubital fossa and the biceps brachii muscle. The distal half of the brachioradialis muscle was included in the flap. The recovery of the elbow was excellent, with a full range of movement. The important conclusion from this case is that the superior perforating branch of the anterior interosseous artery may be used as the basis of an alternative regional flap for the cubital fossa.
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