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Methods for tissue perfusion assessment after Dellon decompression of tarsal tunnels in diabetic neuropathy: key to effective management-a narrative review.
Quant Imaging Med Surg
January 2025
Division of Plastic Surgery, Johns Hopkins University, Baltimore, MD, USA.
Background And Objective: Diabetic neuropathy significantly elevates the risk of foot ulceration and lower-limb amputation, underscoring the need for precise assessment of tissue perfusion to optimize management. This narrative review explores the intricate relationship between sympathetic nerves and tissue perfusion in diabetic neuropathy, highlighting the important role of autonomic neuropathy in blood flow dynamics and subsequent compromises in tissue perfusion. The consequences extend to the development of diabetic peripheral neuropathy and related foot complications.
View Article and Find Full Text PDFRecurrent neurogenic shock as a rare postoperative complication associated with pancreaticoduodenectomy with mesopancreas excision in elderly patient: a case report.
Gland Surg
November 2024
Oncology Center, Sírio-Libanês Hospital, São Paulo, Brazil.
Background: Surgical resection of locally advanced or borderline pancreatic ductal adenocarcinoma is a recognized procedure with curative intent performed in specialized oncology centers. Postoperative dysautonomia such as gastroparesis, mild hypotension, and diarrhea are common in elderly patients undergoing pancreaticoduodenectomy. A distinctive feature of our case, is the severing of an important sympathetic chain by the surgical procedure, leading to recurrent severe neurogenic shock.
View Article and Find Full Text PDFSympathetic NPY ignites adipose tissue.
Neuron
December 2024
NeurObesity Group, Department of Physiology, CIMUS, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), 15706 Santiago de Compostela, Spain. Electronic address:
The established view of hypothalamic neuropeptide Y (NPY) is its orexigenic and weight-promoting effect. A recent article published in Nature by Domingos and colleagues demonstrates that NPY produced by sympathetic neurons protects against obesity by promoting thermogenesis and energy expenditure.
View Article and Find Full Text PDFHeart rate variability in acute pancreatitis: a narrative review.
Transl Gastroenterol Hepatol
August 2024
Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore.
Article Synopsis
- Acute pancreatitis (AP) is a serious condition that can lead to severe complications, making the development of effective prognostic tools essential for timely medical intervention.
- The study explores heart rate variability (HRV) as a potential predictive tool for AP, showing that lower HRV is linked to complications and may outperform traditional scoring systems.
- A comprehensive review of existing literature was conducted to evaluate the relationship between AP and HRV, suggesting that while HRV shows promise, further research is needed to confirm its reliability in clinical settings.
[Research Progress in Neurogram and Neuro-Immune Interaction of Joints in the Case of Osteoarthritis].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
October 2024
Department Five of Orthopedics and Traumatology, Changzhou Hospital of Traditional Chinese Medicine,Changzhou,Jiangsu 213000,China.
The joints have abundant sensory nerves and sympathetic nerve fibers,which convert physical and chemical stimuli in the joints into nerve impulses that are transmitted to the central nervous system and participate in the hypersensitivity reactions of inflammatory joint diseases such as osteoarthritis (OA).This paper summarizes the distribution and functional characteristics of intra-articular nerves and focuses on the mechanism of the vagus-sympathetic autonomic circuit in regulating the immune microenvironment in joints in the case of OA.In addition,intra-articular inflammatory cytokines represented by tumor necrosis factor-α and interleukin-6 directly or indirectly induce sensory nerve action potential and activate the pain transduction pathway from the local joint to the central nervous system.
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