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Repetitive Transcranial Magnetic Stimulation and Tai Chi Chuan for Older Adults With Sleep Disorders and Mild Cognitive Impairment: A Randomized Clinical Trial.
JAMA Netw Open
January 2025
National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Importance: Sleep disorders and mild cognitive impairment (MCI) commonly coexist in older adults, increasing their risk of developing dementia. Long-term tai chi chuan has been proven to improve sleep quality in older adults. However, their adherence to extended training regimens can be challenging.
View Article and Find Full Text PDFAging of Polystyrene Micro/Nanoplastics Enhances Cephalosporin Phototransformation via Structure-Sensitive Interfacial Hydrogen Bonding.
Environ Sci Technol
January 2025
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, P. R. China.
Beyond their roles in adsorbing and transporting pollutants, microplastics (MPs) and nanoplastics (NPs), particularly polystyrene variants (PS-M/NPs), have emerged as potential accelerators for the transformation of coexisting contaminants. This study uncovered a novel environmental phenomenon induced by aged PS-M/NPs and delved into the underlying mechanisms. Our findings revealed that the aged PS-M/NP particles significantly amplified the photodegradation of common cephalosporin antibiotics, and the extent of enhancement was tightly correlated to the molecular structures of cephalosporin antibiotics.
View Article and Find Full Text PDFOptimizing Care for Primary Glomerulonephritis: The Role of Thyroid Evaluation.
Endocr Metab Immune Disord Drug Targets
January 2025
Department of Endocrinology, Metabolism, and Diabetes, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Background: The coexistence of primary glomerulonephritis and autoimmune thyroid disease has not been investigated.
Objective: This study aimed to assess thyroid morphology using sonography, determine the prevalence of autoimmune thyroid disorders, and evaluate thyroid function status in patients diagnosed with primary glomerulonephritis.
Materials And Methods: This single-center cross-sectional and observational study included 58 consecutive patients with primary glomerulonephritis and 58 healthy controls (HC).
Taurodeoxycholate Aggregation Explored by Molecular Dynamics: Primary-To-Secondary Micelle Transition and Formation of Mixed Micelles with Fatty Acids.
Molecules
December 2024
Department of Chemical and Pharmaceutical Engineering, Faculty of Chemistry and Pharmacy, University of Sofia, 1164 Sofia, Bulgaria.
Micelles formed by bile salts in aqueous solution are important for the solubilization of hydrophobic molecules in the gastrointestinal tract. The molecular level information about the mechanism and driving forces for primary-to-secondary micelle transition is still missing. In the current study, the micelle formation of 50 mM solutions of taurodeoxycholate (TDC) is studied by atomistic molecular dynamics simulations.
View Article and Find Full Text PDFEffect of Solution Treatment on the Microstructure and Elevated Temperature Tensile Properties of Forged Rene 41 Superalloy.
Materials (Basel)
December 2024
Chengdu Advanced Metal Materials Industrial Technology Institute Co., Ltd., Chengdu 610300, China.
The effects of a solution treatment on the microstructure and elevated mechanical properties of the forged Rene 41 superalloy were investigated. The results indicate that the solution treatment temperature has a significant influence on the γ' structure and mechanical properties. The sub-solvus solution treatment resulted in the co-existence of residual primary coarse γ' precipitates and fine secondary γ' precipitates, while the super-solvus solution treatments led to the complete dissolution of the primary γ' precipitates and the precipitation of a nano-sized secondary spherical γ' precipitate.
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