For the past decade, federal judges have been obligated to serve as gatekeepers and keep scientifically unreliable and irrelevant expert testimony out of the courtroom. The exacting evidentiary standards set forth in the landmark Daubert decision have had a significant impact on numerous areas of legal dispute. Toxic tort litigation, in particular, has been transformed by the standards. This Article reviews the Supreme Court's adoption of the scientific method as the standard for admissibility of expert testimony. It analyzes how a court's proper understanding of the scientific method can guide it in evaluating the different types of causation evidence presented in toxic tort litigation, both with respect to general and specific causation. Throughout this discussion and in the concluding section, the Article reflects the authors' firm's experience as national defense counsel in a series of product liability cases involving the prescription drug Parlodel, in which these evidentiary issues have been analyzed extensively.
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Chempluschem
January 2025
Department of Chemical Engineering, Indian Institute of Science Education and Research Bhopal, Bhopal, 462066, Madhya Pradesh, India.
The agricultural sector of any country plays a pivotal role in its economy. Irrigation and the provision of appropriate nutrient levels in soil are essential for optimizing plant growth and enhancing crop productivity. To support the increasing need for food due to the growing population worldwide, synthetic fertilizers have been widely used in the agricultural sector.
View Article and Find Full Text PDFJ Gastroenterol Hepatol
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background And Aim: Colorectal cancer (CRC) is a significant global health burden, and screening can greatly reduce CRC incidence and mortality. Previous studies investigated the economic effects of CRC screening. We performed a systematic review to provide the cost-effectiveness of CRC screening strategies across countries with different income levels.
View Article and Find Full Text PDFAnal Chem
January 2025
Department of Nature Sciences, Mathematics and Education, Federal University of São Carlos, 13600-970 Araras, São Paulo, Brazil.
A few decades ago, the technological boom revolutionized access to information, ushering in a new era of research possibilities. Electrochemical devices have recently emerged as a key scientific advancement utilizing electrochemistry principles to detect various chemical species. These versatile electrodes find applications in diverse fields, such as healthcare diagnostics and environmental monitoring.
View Article and Find Full Text PDFLuminescence
January 2025
Department of Chemistry, College of Science, Jouf University, Sakaka, Aljouf, Saudi Arabia.
In the present study, a norfloxacin (NFX) fluorescent probe was tailored for the spectrofluorometric measurement of cefepime (CFP). The proposed approach measured the quenching effect of CFP on the fluorescence intensity of NFX in acetate buffer solution. The obtained results show that CFP strongly quenches the fluorescence of NFX in a static mechanism.
View Article and Find Full Text PDFOrg Lett
January 2025
School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, Hunan 411201, China.
An unprecedented synergistic copper- and amine-catalyzed cyclization of enynone is reported. This reaction features an efficient and straightforward construction of multisubstituted tetralone through an amine-assisted regioselective oxygen atom transfer process and stereoselective intramolecular Michael addition cyclization. Under dehydrative reaction conditions, the synthesis of tetrahydronaphthylimine derivatives with ketone group tolerance is achieved, which could be challenging via traditional methods.
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