A prevalence survey of onchoceriasis was done in Kabarole district, Uganda, in 1990. The objective was to determine the prevalence of onchocerciasis among communities living in previously known foci. A total number of 1186 persons was included in the study. The infection rate among the communities studied ranged from 0% to 67%. The most frequent clinical signs and symptoms of onchocerciasis were: pruritus (80%), rough skin (46%), skin rash (30%), leopard skin (6%) and sclerosing keratitis (7%). 3.6% of all cases with onchocercasis were found to have no perception of light. The total number of cases in the district was estimated to be 32,000. The study showed that the foci, where Simulium neavei is the vector, are still active. In contrast, very few infections with Onchocerca volvulus were found in the Rwenzori focus, where S. damnosum s. 1. was the vector. The results indicate that onchocerciasis is of public health importance in Kabarole district and needs to be controlled.
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Am J Trop Med Hyg
December 2024
Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA.
PLoS One
May 2024
Division of Pulmonary and Critical Care Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America.
Background: The high case-fatality rates among children with tuberculosis (TB) are reportedly driven by in-hospital mortality and severe forms of TB. Therefore, there is need to better understand the predictors of mortality among children hospitalised with TB. We examined the patient clinical profiles, length of hospital stay from date of admission to date of final admission outcome, and predictors of mortality among children hospitalised with TB at two tertiary hospitals in Uganda.
View Article and Find Full Text PDFAnimals (Basel)
December 2023
Department of Production Animal Studies (DPAS), Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South Africa.
African swine fever (ASF) is a haemorrhagic fever of swine that severely constrains pig production, globally. In Uganda, at least 388 outbreaks of ASF were documented from 2001 to 2012. We undertook a retrospective serological and molecular survey of ASF virus (ASFV) using banked samples collected from seven districts (Pallisa, Lira, Abim, Nebbi, Kabarole, Kibaale, and Mukono) of Uganda.
View Article and Find Full Text PDFAm J Trop Med Hyg
July 2023
Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Alcohol-based hand rub (ABHR) is an effective hand hygiene measure to mitigate and prevent infectious disease transmission in healthcare facilities (HCFs); however, availability and affordability in low- and middle-income countries are limited. We sought to establish centralized local production of ABHR using a district-wide approach to increase provider access at all public HCFs in Kabarole and Kasese Districts in Western Uganda. Partner organizations worked with district governments to adapt and implement the WHO protocol for local ABHR production at the district scale.
View Article and Find Full Text PDFClin Hypertens
April 2023
Division of Global Health Protection, Centers for Disease Control and Prevention, Kampala, Uganda.
Background: High blood pressure (HBP), including hypertension (HTN), is a predictor of cardiovascular events, and is an emerging challenge in young persons. The risk of cardiovascular events may be further amplified among people living with HIV (PLHIV). We determined the prevalence of HBP and associated factors among PLHIV aged 13 to 25 years in Rwenzori region, western Uganda.
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