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Are Oral Somatostatin Receptor Ligands Moving Closer to Becoming a Reality?
Clin Endocrinol (Oxf)
December 2024
Departments of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK.
With the current therapeutic modalities available to endocrinologists, control of GH and IGF-I is now possible in almost all patients with acromegaly with multi-modality therapy. Despite biochemical control of GH and IGF-I, patients with acromegaly continue to experience impaired quality of life. Although there are likely multiple factors contributing to this dissatisfaction with current medical therapies, in particular the widely utilised injectable long-acting somatostatin receptor ligands (iSRL), is a contributor.
View Article and Find Full Text PDFEvaluation of an interprofessional collaborative practice training module for the management of children with autism spectrum disorder.
Med J Armed Forces India
December 2024
Professor (Microbiology), Director, MAHE-FAIMER Institute, Manipal Academy of Higher Education, Manipal, India.
Background: Protocols instituted for behavioral treatment and skills training programs for the management of autism spectrum disorder (ASD) suffer from lack of collaborative approaches. The tenets of interprofessional collaborative practice (IPCP) focus on preparing a panel of health care professionals (HCPs) from different professions who can work together to enable the common goal of ensuring that children with ASD can participate in society. This study was designed to pilot this approach through an IPCP training module on ASD for care providers from multiple professions.
View Article and Find Full Text PDFA novel and alternative treatment method for moderate diabetic foot ulcer: tibial periosteal distraction.
J Orthop Surg Res
December 2024
Diabetic Foot Treatment Centre, Peking University People's Hospital, Peking University, Beijing, China.
Objective: Researchers have proposed a novel surgical treatment for moderate diabetic foot ulcer: tibial periosteal distraction (TPD) which could improve affected limb microcirculation. We aimed to describe the method and therapeutic effects of this technique.
Methods: We provided a technical guide to perform TPD surgery for the treatment of moderate diabetic foot ulcer of who had been treated in our department.
Spectroscopic approach to optimize the biogenic silver nanoparticles for photocatalytic removal of ternary dye mixture and ecotoxicological impact of treated wastewater.
Sci Rep
December 2024
Department of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, 144411, India.
The fabricating of extremely effective, economical, ecologically safe, and reusable nanoparticle (NP) catalysts for the removal of water pollution is urgently needed. This study, spectroscopically optimizes the process parameters for the biogenic synthesis of AgNP catalysts using Cledrdendrum infortunatum leaf extract. The optimization of several synthesis parameters was systematically studied using UV-Vis spectroscopy to identify the ideal conditions for AgNPs formation.
View Article and Find Full Text PDFExploring residents' perspectives on their professional identity in general practice residency in the Netherlands: a qualitative study.
BMJ Open
December 2024
Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands.
Objectives: Educational initiatives in residency may lack alignment with residents' learning objectives. Furthermore, they may overlook residents' struggle to find fulfilment in their work. Professional identity formation (PIF) is a conceptual lens through which to explore the alignment of educational initiatives with residents' learning objectives.
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