AI Article Synopsis
- The study investigates the potential of using long-term stored serum in human in vitro production, focusing on its supply of essential nutrients.
- Mouse embryos were tested with serum that had been stored for 1, 5, 10, and 12 years, with consistent results across all time periods.
- The findings indicate that serum can be safely frozen and utilized for up to 12 years without significant impact on embryo development.
Article Abstract
Purpose: To determine the viability of long-term, stored serum, which is used in human in vitro production as a source of energy substrates, amino acids, vitamins, growth factors, and other nutrients.
Method: Two-cell mouse embryos were used in this prospective, cohort study. Serum stored for 1-, 5-, 10-, and 12-year intervals was subjected to four replications of mouse-embryo testing.
Result(s): There were no significant differences in blastocyst rates between any of the replicates by year (80-100% blastocyst rate; P > 00.1) or between pooled replicate means by time period.
Conclusion(s): Serum may be frozen up to 12 years.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455446 | PMC |
| http://dx.doi.org/10.1023/b:jarg.0000025938.67218.47 | DOI Listing |
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