Obesity in children and adolescents has reached alarming proportions in the United States. Nutritional surveys do not indicate a significant increase in caloric intake in children and adolescents over the last 3 decades, although caloric intake has increased recently in adolescent females. Dietary fat has also been falling. There is no conclusive evidence linking physical inactivity to the obesity epidemic, and longitudinal studies indicate that physical inactivity may be the result of obesity rather than its cause. Hence, attention should be focused on dietary carbohydrate. Carbohydrate intake has increased as a result of the decrease in dietary fat. Indirect evidence also indicates that the quality of carbohydrate has been changing, so that American children are eating more carbohydrates with a higher glycemic index. It is proposed that high-glycemic-index diets lead to excessive weight gain as a consequence of postprandial hyperinsulinemia. Low-glycemic-index diets lower postprandial insulin levels and insulin resistance. It seems likely that diets restricted in sweetened sodas and noncitrus juices and containing ample whole grains, vegetables, and fruit could have a major impact on the prevalence of pediatric obesity.
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http://dx.doi.org/10.1210/jc.2003-031449 | DOI Listing |
Physiol Genomics
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of Granada, Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain.
We examined the effects of a 20-week exercise intervention on whole-blood genome-wide DNA methylation signature and its association with the exercise-induced changes in gene expression profiles in boys and girls with overweight/obesity (OW/OB). Twenty-three children (10.05 ± 1.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
January 2025
Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Stony Brook Children's Hospital, Stony Brook, USA.
Objectives: To determine if after 2 years of consuming a gluten-free diet post celiac disease diagnosis, pediatric patients who were overweight or obese at diagnosis are less likely to normalize celiac disease serologies as compared with those who were normal weight or underweight at diagnosis. Secondary aims include characterizing how initial symptoms at presentation predict body mass index (BMI) change and serology improvement over the first 2 years of being on a gluten-free diet following diagnosis of celiac disease.
Methods: A retrospective chart review was performed that included all biopsy-proven celiac disease patients followed at Stony Brook Children's Hospital's Celiac Disease Center diagnosed between the years 2007-2022.
Front Psychiatry
December 2024
Institute of Medical Psychology, Faculty of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.
Background: As placebo interventions could influence appetite and satiety in first studies, they are a promising tool for the future treatment of obesity. Furthermore, individuals with heightened body weight show increased selective attention for food cues. This study aimed to investigate whether placebo induced changes of appetite and satiety can affect attention allocation and to examine correlating factors.
View Article and Find Full Text PDFGut Liver
January 2025
Department of Radiology, Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
Background/aims: To evaluate the associations between pediatric fatty liver severity, bioelectrical impedance analysis (BIA), and magnetic resonance imaging parameters, including total psoas muscle surface area (tPMSA) and paraspinal muscle fat (PMF).
Methods: Children and adolescents who underwent BIA and liver magnetic resonance imaging between September 2022 and November 2023 were included. Linear regression analyses identified predictors of liver proton density fat fraction (PDFF) including BIA parameters, tPMSA, and PMF.
J Health Popul Nutr
January 2025
Research Center for Non-Communicable Disease, Jahrom University of Medical Sciences, Jahrom, Iran.
Background: Malnutrition, wasting, and obesity among children under 6 years old pose a serious global health concern, increasing the risk of various infectious and non-infectious diseases. Therefore, regular monitoring of these conditions is crucial. This study aimed to evaluate the prevalence of malnutrition in children under 6 years of age from 2018 to 2023.
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