[Clinical observation of "dan shao tang" in treating mesangial proliferative glomerulonephritis of deficiency of yin with damp-heat symptom].

Objective: To explore the effect of "Dan Shao Tang" (DST) on mesangial proliferative glomerulonephritis (MsPGN) of deficiency of Yin with damp-heat symptom.

Methods: 90 patients with MsPGN of deficiency of Yin with damp-heat symptom were randomly divided into two groups. 54 patients in treatment group were treated with DST and western medicine, and 36 patients in control group were treated only with western medicine. We observed the effect and indexes change including renal function, proteinuria, hematuria, lipid before and after treatment.

Results: After three months treatment, the general effective rate in treatment group was 75.93%, which was markedly higher than that in control group (47.22%, P < 0.01). Treatment group is obviously better than control group on decreasing proteinuria and hematuria, improving renal function, ameliorating lipid metabolism (P < 0.05).

Conclusion: DST is effective on MsPGN of deficiency of Yin with damp-heat symptom.