Microwave-accelerated SPOT-synthesis on cellulose supports.

Org Lett

Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, USA.

Published: June 2004

[reaction: see text] We demonstrate that microwave irradiation can dramatically accelerate reaction rates for spatially addressable library synthesis on planar membrane supports. The development of a robust support/linker system, microwave-assisted synthesis of small molecule test libraries, and methods for solid-phase scale-up on cellulose are described.

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol049313fDOI Listing

Publication Analysis

Top Keywords

microwave-accelerated spot-synthesis
4
spot-synthesis cellulose
4
cellulose supports
4
supports [reaction
4
[reaction text]
4
text] demonstrate
4
demonstrate microwave
4
microwave irradiation
4
irradiation dramatically
4
dramatically accelerate
4

Similar Publications

Microwave-accelerated SPOT-synthesis on cellulose supports.

Org Lett

June 2004

Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, USA.

[reaction: see text] We demonstrate that microwave irradiation can dramatically accelerate reaction rates for spatially addressable library synthesis on planar membrane supports. The development of a robust support/linker system, microwave-assisted synthesis of small molecule test libraries, and methods for solid-phase scale-up on cellulose are described.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!