AI Article Synopsis
- DNA damage response mechanisms are critical for maintaining accurate chromosomal transmission, and their failure can result in premature aging and cancer.
- A recent study has found that casein kinase 2 (CK2) regulates the DNA repair protein XRCC1, highlighting its role in DNA repair processes.
- These findings suggest that CK2 is a vital component of the cellular response to DNA damage.
Article Abstract
DNA damage response mechanisms help ensure the fidelity of chromosomal transmission, and the failure of such mechanisms might lead to premature aging and cancer. A new report has established that casein kinase 2 (CK2), a protein that functions in diverse cellular processes, controls the activity of the DNA repair protein XRCC1. These results indicate that CK2 is a key participant in the cellular response to DNA damage.
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| http://dx.doi.org/10.1126/sageke.2004.22.pe24 | DOI Listing |
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