Heeding clues to giant cell arteritis. Prompt response can prevent vision loss.

Postgrad Med

Department of Medicine, University of Miami School of Medicine, PO Box 016960 (R-103), Miami, FL 33101, USA.

Published: May 2004

AI Article Synopsis

  • A 74-year-old woman with new headaches, anemia, and elevated ESR may have giant cell arteritis, a serious condition.
  • Vision loss is a major early complication to watch for.
  • Immediate treatment with corticosteroids and a temporal artery biopsy are necessary, along with careful monitoring of her symptoms and lab results.

Article Abstract

To return to the case vignette, the new onset of headache in a 74-year-old woman with anemia and a markedly elevated ESR should alert the physician to the strong possibility of giant cell arteritis. Vision loss is the most significant potential early complication. Temporal artery biopsy is indicated, and treatment with corticosteroids should be started immediately. Close monitoring of the patient's symptoms and laboratory parameters is critical, as is surveillance for potential late complications.

Download full-text PDF

Source
http://dx.doi.org/10.3810/pgm.2004.05.1517DOI Listing

Publication Analysis

Top Keywords

giant cell
8
cell arteritis
8
vision loss
8
heeding clues
4
clues giant
4
arteritis prompt
4
prompt response
4
response prevent
4
prevent vision
4
loss return
4

Similar Publications

Case report: a case of AL amyloidosis with spontaneous giant retroperitoneal hematoma.

Int J Emerg Med

December 2024

Emergency Department, The State Key Laboratory for Complex, Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

Background: Systemic amyloidosis is a kind of clinical syndrome in which amyloid is deposited between the cells of various organs in the body, resulting in gradual failure of the function of the affected organs. Depending on the site of amyloid deposition, it may show various clinical symptoms of multiple system involvement.

Patient Concerns: A 44-years-old female with spontaneous giant retroperitoneal hematoma was admitted to the emergency department of Peking Union Medical College Hospital in Mar 2023.

View Article and Find Full Text PDF

We present novel fluorescent cholesteryl probes (CNDs) with a modular design based on the solvatochromic 1,8-phthalimide scaffold. We have explored how different modules-linkers and head groups-affect the ability of these probes to integrate into lipid membranes and how they distribute intracellularly in mouse astrocytes and fibroblasts targeting lysosomes and lipid droplets. Each compound was assessed for its solvatochromic behavior in organic solvents and model membranes.

View Article and Find Full Text PDF

Acute promyelocytic leukaemia (APL) is a highly lethal haematological malignancy. It is rare in pregnancy and may be fatal if not managed promptly and appropriately. A woman in her 20s presented with high-grade fever at 16 weeks of her third pregnancy.

View Article and Find Full Text PDF

Cell-free systems, which can express an easily detectable output (protein) with a DNA or mRNA template, are promising as foundations of biosensors devoid of cellular constraints. Moreover, by encasing them in membranes such as natural cells to create artificial cells, these systems can avoid the adverse effects of environmental inhibitory molecules. However, the bacterial systems generally used for this purpose do not function well at ambient temperatures.

View Article and Find Full Text PDF

Modern radiotherapy utilizes a broad range of sources of ionizing radiation, both low-dose-rate (LDR) and high-dose-rate (HDR). However, the mechanisms underlying specific dose-rate effects remain unclear, especially for corpuscular radiation. To address this issue, we have irradiated human epidermoid carcinoma A431 cells under LDR and HDR regimes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!