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The Silent Epidemic: Unveiling Herpetic Uveitis in the Elderly.
J Med Virol
March 2025
Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
In aging societies, uveitis-a leading cause of vision loss due to ocular inflammation-is increasingly prevalent, especially among older people. This study aimed to determine the trends and contributing factors of herpetic uveitis in older people, reflecting the broader impact of demographic shifts on ocular health. A retrospective study at the Institute of Science Tokyo reviewed uveitis cases in patients aged ≥ 65 years between 2012 and 2022.
View Article and Find Full Text PDFHand Arm Vibration Syndrome [HAVS]: What Do We Know So Far? - Journal Review.
Ortop Traumatol Rehabil
August 2024
Szpital Miejski św. Jana Pawła II w Elblągu, Polska / St. John Paul II Municipal Hospital in Elblag, Poland.
Background: Since over century it has been known that hand to arm transmitted vibrations (HAV) can affect health and quality of life. Exposure over certain level and intensity over time are risk causes of Hand Arm Vibration Syndrome (HAVS). Symptoms varies from the damaged structures which most commonly are secondary Raynaud Phenomenon known as Vibration Induced White Finger (VWF), carpal tunnel syndrome, tingling, loss of manual dexterity, osteoarthritis or even Dupuytren's contracture.
View Article and Find Full Text PDFPortal vein velocity and its dynamics: a potentially useful tool for detecting clinically silent transjugular intrahepatic porto-systemic shunt dysfunction using Doppler ultrasonography.
Ultrasound Int Open
December 2024
Internal Medicine Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Ultrasound (US) surveillance for transjugular intrahepatic portosystemic shunt (TIPS) dysfunction has yet to be standardized, as clear-cut criteria have not been conventionally defined. This study evaluated the role of US-based parameters in detecting hemodynamic TIPS dysfunction (HD). We included consecutive patients treated with TIPS.
View Article and Find Full Text PDFDirect Cloning and Heterologous Expression of the Dmxorosin Biosynthetic Gene Cluster from SPC6, a Halotolerant Actinomycete Isolated from the Desert in China.
Int J Mol Sci
February 2025
State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
SPC6 is a halotolerant strain isolated from the Linze Desert in China. It has a very high growth rate and short life cycle compared to other Streptomycetes, including the model organism The one strain-many compounds fermentation approach and global natural products investigation revealed that SPC6 exhibits impressive productivity of secondary metabolites. Genome mining uncovered 20 typical secondary metabolic biosynthetic gene clusters (BGC), with a BGC identified as completely silent.
View Article and Find Full Text PDFOsteoporosis: Relevance of Biomolecules for Diagnosis and Treatment.
Curr Med Chem
February 2025
Council for Nutritional and Environmental Medicine (CONEM), Mo i Rana, Norway.
Osteoporosis, a metabolic disorder distinguished by decreased bone density and degradation of bone tissue microarchitecture, is a silent disease that evolves without any clinical symptoms or signs. An individual may not be aware of osteoporosis until a fracture occurs. The lifetime risk of osteoporosis is estimated to be between 10 and 20%.
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