Our study make a comparative analysis of biological properties of glucosyltranterases(GTF) secreted by S.sanguis 34 and S.mutans Ingbritt(c).The results as follows:(1)S.sanguis 34 has more extractions of extracelluar GTF than S.mutans Ingbritt(c) under equal cultured conditions,but S.mutans Inggbritt(c) has more activity of extracelluar GTF than S.sanguis.These differences are identical with the difference of their cariogenicities;(2)GTF of S.sanguis 34 can also synthesize water-soluble glucan,and is a multienzyme complex system as S.mutans. S.sanguis might catalyse sufficient dextran formation to stimulate the primer-dependent activity of the S.mutans GTF enzyme. This might aid the adhesion of this comparatively late colonizer;(3)easier to obstruct high pure GTF of S.sangusi 34 S.mutans.

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