The influences of trace elements lanthanum,cerium and fluorine to the activity of clostridium histolyticum collagenase(CHC) during the period of CHC degrading the cemental root collagen in vitro is studied.The results reveal that La(3+) can significantly inhibit the activity of the CHC than Ce(3+) and F(-). Therefore it suggests that lanthanum may be used as a new kind of element in preventing root caries.The mechanisms of above functions are also discussed.
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