The concept of the metabolic syndrome has now been in existence for several decades; however, it has only been since some agreement on definitions of the syndrome was reached that it has been possible to compare the prevalence among populations worldwide. Just as the prevalence of the individual components of the syndrome varies among populations, so does the prevalence of the metabolic syndrome itself. Differences in genetic background, diet,levels of physical activity, population age and sex structure, levels of over- and undernutrition, and body habitus all influence the prevalence of both the metabolic syndrome and its components. Regardless of the underlying genetic and environmental influences that mediate the prevalence of the metabolic syndrome, a higher prevalence will undoubtedly lead to undesirable outcomes such as cardiovascular disease.
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http://dx.doi.org/10.1016/j.ecl.2004.03.005 | DOI Listing |
PLoS One
January 2025
Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.
Introduction: 22q11 deletion syndrome (22q11DS) results from a microdeletion on chromosome 22 and is the most common microdeletion disorder in humans, affecting 1 in 2148 live births. Clinical manifestations vary widely among individuals and across different life stages. Effective management requires the involvement of a specialized multidisciplinary team.
View Article and Find Full Text PDFPLoS One
January 2025
School of Nursing, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Background: Time-restricted eating (TRE) manages weight effectively, but choosing how long and what time window remain debatable. Although an 8:00 a.m.
View Article and Find Full Text PDFBackground: Prostatic malignancy with paraneoplastic subacute encephalitis -A rare syndrome METHOD: We present a case of 76 year old male without any previous comorbidity and addiction who manifested a rapid neuropsychiatric decline with a frontotemporal syndrome over a period of 6 months. He was anemic and cerebrospinal fluid study showed 10 cells with lymphocytic predominance. The extensive workup of csf for infection, malignancy revealed nothing.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Background: The Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is one of the biggest health concerns of the century. Long COVID is one of the major sequelae from the infection and include persistent neurological manifestations. Brain images study suggest that Long COVID patients present distinct brain metabolic alterations.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Background: To date, limited data exist concerning the utility of FDG-PET in detecting Alzheimer's Disease (AD) in Down Syndrome (DS). Yet, sensitive biomarkers for neurodegeneration are essential in this population genetically predisposed for AD. Therefore, we aimed at characterizing the effect of age, disease stage and AD pathology on brain metabolism in a large cohort of adults with DS.
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