AI Article Synopsis
- eNOS is found in peripheral nerve fibers of rat palates, particularly in the glandulae palatinae.
- Phosphorylation at Ser(116) was confirmed, while Ser(1177) and Thr(495) phosphorylation were not detected in these fibers.
- The study concludes that eNOS is primarily phosphorylated at Ser(116) under normal conditions in these nerve fibers, with no evidence of Ser(1177) and Thr(495) phosphorylation.
Article Abstract
It is known that total endothelial nitric oxide synthase (eNOS) is localized in peripheral nerve fibers, but the existence of the phosphorylation site/s of eNOS in peripheral nerve fibers is unknown. In the perfusion-fixed and decalcified sections of rat palates, eNOS and eNOS phosphorylated at Ser(116) were identified in the nerve fibers of the glandulae palatinae. The localization of eNOS phosphorylated at Ser(1177) and Thr(495) in nerve fibers was undetectable. It is concluded that eNOS is phosphorylated at Ser(116) in nerve fibers of the glandulae palatinae under basal conditions. The basal Ser(1177) and Thr(495) phosphorylation of eNOS are missing in nerve fibers of the glandulae palatinae.
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| http://dx.doi.org/10.1016/j.neulet.2004.03.045 | DOI Listing |
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