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Proactive esophageal cooling during radiofrequency cardiac ablation: data update including applications in very high-power short duration ablation.
Expert Rev Med Devices
January 2025
Cardiac Electrophysiology, NorthShore University Health System, Evanston, IL, USA.
Introduction: Proactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4 s. Varying power and duration, however, does not eliminate the risk of thermal injury.
View Article and Find Full Text PDFChoice Matters: The Moderating Effect of Choice on the Relationship Between Mental Health Personal Recovery and Symptomatology.
J Adolesc Health
February 2025
Silver School of Social Work, New York University, New York, New York.
Purpose: Limited research examines how choice surrounding treatment impacts mental health recovery among young adults with serious mental illness (SMI) who are navigating symptom management, complex mental health systems, and developmental expectations of increased independence. This study examines whether perceived choice related to mental health treatment impacts the relationship between symptomatology and personal recovery among Black, Latino/e, and multiracial young adults with SMI.
Methods: Surveys were conducted with 121 young adults with SMI attending a community-based personal recovery-oriented program.
Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers.
Alzheimers Dement
October 2024
Department of Neurology, University of California, San Francisco, Memory and Aging Center, San Francisco, California, USA.
Article Synopsis
- - Cardiovascular health, evaluated through Life's Simple 7 (LS7), is linked to slower cognitive decline and better brain integrity in patients with autosomal dominant frontotemporal lobar degeneration (FTLD).
- - A study involving 247 FTLD genetic variant carriers and 189 non-carrier controls found that those with better cardiovascular health had slower memory and language declines, as well as less accumulation of frontal white matter hyperintensities (WMHs).
- - Maintaining good cardiovascular health could be a key modifiable strategy to improve cognitive outcomes and brain health in individuals at risk for genetic forms of dementia.
Routine closed-suction drainage reduces seromas following totally extraperitoneal (TEP) inguinal hernia repair: A meta-analysis.
Medicine (Baltimore)
March 2024
Heinrich-Heine-University and University Hospital Duesseldorf, Department of Surgery (A), Duesseldorf, Germany.
Background: The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes.
Methods: A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement.
Prediction of Effectiveness and Toxicities of Immune Checkpoint Inhibitors Using Real-World Patient Data.
JCO Clin Cancer Inform
February 2024
Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN.
Purpose: Although immune checkpoint inhibitors (ICIs) have improved outcomes in certain patients with cancer, they can also cause life-threatening immunotoxicities. Predicting immunotoxicity risks alongside response could provide a personalized risk-benefit profile, inform therapeutic decision making, and improve clinical trial cohort selection. We aimed to build a machine learning (ML) framework using routine electronic health record (EHR) data to predict hepatitis, colitis, pneumonitis, and 1-year overall survival.
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