We investigated the biological properties of a novel staphylococcal enterotoxin-like putative toxin, staphylococcal enterotoxin-like toxin type R (SElR). Major histocompatibility complex class II molecules were required for T-cell stimulation by SElR. SElR stimulated T cells bearing receptors Vbeta 3, 11, 12, 13.2, and 14. These results suggested that SElR acts as a superantigen.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC415704 | PMC |
http://dx.doi.org/10.1128/IAI.72.6.3664-3667.2004 | DOI Listing |
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