The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans.

Infect Immun

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Published: June 2004

Cryptococcus neoformans is a human fungal pathogen that has two mating types (a and alpha). Experiments have shown that in some backgrounds alpha strains are more virulent than a strains. Our studies reveal that the only known alpha-specific factor, SXI1alpha, is not necessary for virulence.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC415721PMC
http://dx.doi.org/10.1128/IAI.72.6.3643-3645.2004DOI Listing

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