Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/429241a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification of a nuclear matrix attachment region like sequence in the last intron of PI3Kgamma.
Biochem Biophys Res Commun
March 2006
Department of Biochemistry and Molecular Biology, Shanghai Second Medical University, Shanghai 2000 25, PR China.
MARs are not only the structure bases of chromatin higher order structure but also have much biological significance. In this study, the whole sequence of about 100 kb in length from BAC clone of GS1-223D4 (GI: 5931478), in which human PI3Kgamma gene is localized, was analyzed by two online-based computer programs, MARFinder and SMARTest. A strong potential MAR was predicted in the last and largest intron of PI3Kgamma.
View Article and Find Full Text PDFIn silico prediction of scaffold/matrix attachment regions in large genomic sequences.
Genome Res
February 2002
Genomatix Software, D-80339 München, Germany.
Scaffold/matrix attachment regions (S/MARs) are essential regulatory DNA elements of eukaryotic cells. They are major determinants of locus control of gene expression and can shield gene expression from position effects. Experimental detection of S/MARs requires substantial effort and is not suitable for large-scale screening of genomic sequences.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!