Aim: To investigate the effect of momordica anti-HIV protein of M(r ) being 30 000 (MAP30) on HBV expression by laser scanning confocal microscopy.
Methods: HBV DNA-transfected hepatocarcinoma cells 2.2.15 were cultured in the presence of MAP30. Then quantitative analysis of HBeAg expression in the 2.2.15 cells by laser scanning confocal microscopy after indirect immunofluorescence staining was performed.
Results: The fluorescence intensity in 2.2.15 cells co-cultured with MAP30 was notably weaker than that in control cells.
Conclusion: MAP30 can effectively inhibit HBeAg expression in the 2.2.15 cells.
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