The Butyrivibrio fibrisolvens tet(W) gene is located on the conjugative transposon TnB1230. TnB1230 encodes transfer proteins with 48 to 67% identity to some of those encoded by Tn1549. tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC415762PMC
http://dx.doi.org/10.1128/JB.186.11.3656-3659.2004DOI Listing

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