Neonatal hyperbilirubinemia and jaundice affect approximately 60% of the 4 million newborns in the United States each year. Jaundice results from bilirubin deposition in the skin and mucous membranes, becoming clinically visible at a serum bilirubin level of 5 to 7 mg/dL. At a higher but undefined level, bilirubin may deposit in the brain where it can cause transient dysfunction or permanent neurologic impairment.
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| http://dx.doi.org/10.1016/j.ccell.2004.02.010 | DOI Listing |
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