Research in brain-damaged patients has suggested that the right hemisphere plays a role in unilateral spatial neglect (USN), but provides only limited information for pinpointing the intraparietal localization of the lesions associated with this syndrome. We report a case of unilateral neglect in a patient who underwent a right inferior parietal cortectomy for refractory epilepsy without any macroscopic lesion. We describe the evolution of the neuropsychological disturbances observed at 3 and 24 months after cortectomy. This case illustrates the role played by the inferior parietal lobe and, particularly, the parietal opercule in USN syndrome, and provides strong "experimental" evidence of the special role played by the inferior parietal lobule in the perception processes related to spatial attention.
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http://dx.doi.org/10.1016/j.yebeh.2004.02.008 | DOI Listing |
J Neurophysiol
January 2025
The Neuroimaging Research Group, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN, 55417, USA.
Performance of a task involves the engagement of various brain areas, as evidenced by the effects of lesions of particular brain areas and the results of functional neuroimaging and neurophysiological studies. Here we tested the hypothesis that overall task performance would depend on the level of ongoing, resting-state change in synaptic activity of participating areas, such that the degree of success of the outcome would be higher, the higher the resting-state activation. For that purpose, we used 248-sensor magnetoencephalography (MEG) in healthy people to obtain estimates of resting-state synaptic activity in various areas and then correlated those estimates to the average performance score in three visuospatial tasks assessed outside the MEG session using the Montreal Cognitive Assessment (MoCA), namely the Trails, Cube, and Clock Drawing (TCCD) tasks.
View Article and Find Full Text PDFNat Sci Sleep
January 2025
Department of Radiology, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, People's Republic of China.
Background: COVID-19 has led to reports of fatigue and sleep problems. Brain function changes underlying sleep problems (SP) post-COVID-19 are unclear.
Purpose: This study investigated SP-related brain functional connectivity (FC) alterations.
Neurol Sci
January 2025
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder ranging from mild cognitive impairment (MCI) to AD dementia. Abnormal cerebral perfusion alterations, influenced by amyloid-beta (Aβ) accumulations, have been implicated in cognitive decline along this spectrum.
Objective: This study investigates the relationship between cerebrospinal fluid (CSF) Aβ1-42 levels and regional cerebral blood flow (CBF) changes across the AD continuum using the Arterial Spin Labeling (ASL) technique.
Hum Brain Mapp
February 2025
Université libre de Bruxelles (ULB), UNI - ULB Neuroscience Institute, Laboratoire de Neuroanatomie et Neuroimagerie translationnelles (LN2T), Brussels, Belgium.
Language control processes allow for the flexible manipulation and access to context-appropriate verbal representations. Functional magnetic resonance imaging (fMRI) studies have localized the brain regions involved in language control processes usually by comparing high vs. low lexical-semantic control conditions during verbal tasks.
View Article and Find Full Text PDFNeuropsychologia
January 2025
Centre for Cognitive Neuroscience, Department of Psychology, University of Salzburg, Austria.
Neuroscience has examined the brain processes of recognizing and identifying a known person. But the process of integrating the representation of a temporarily unrecognised person with the representation of the familiar person is not yet known (e.g.
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