We have shown signs of behavioral depression after vibrissal deafferentation. Locomotor slowing, motor impairments and footshock thresholds increment were demonstrated after vibrissal afferent blockages. Here, we study the electrocortical (ECoG) effects of vibrissal pad anaesthesia, also replicated by bilateral brachial plexus blockage. We found in both cases, that this acute and massive deafferentation produces synchronization over the entire neocortex accompanied by an important loss of muscular electrical activity. Slow waves observed in this condition were similar to those recorded in the sleeping rat without any treatment, but in our case, there were no behavioral signs of sleep. Thus a clear behavioral electroencephalographic dissociation was obtained by acute deafferentation. These results would seem to support the sleep deafferentation hypothesis.
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Blockage of vibrissal afferents: III. Electrocorticographic effects.
Arch Ital Biol
February 2004
Cátedra de Neurociencia, Facultad de Medicina, Universidad Nacional de Tucumán, Dpto. Fisiología y Neurociencia, INSIBIO, CONICET, Tucumán, Argentina.
We have shown signs of behavioral depression after vibrissal deafferentation. Locomotor slowing, motor impairments and footshock thresholds increment were demonstrated after vibrissal afferent blockages. Here, we study the electrocortical (ECoG) effects of vibrissal pad anaesthesia, also replicated by bilateral brachial plexus blockage.
View Article and Find Full Text PDFBlockage of vibrissae afferents: II. Footshock threshold increments.
Arch Ital Biol
February 2004
Cátedra de Neurociencia, Facultad de Medicina, Universidad Nacional de Tucumán, Dpto. Fisiología y Neurociencia, INSIBIO, CONICET, Tucumán, Argentina.
Because of their dense innervation rat vibrissae have been regarded as a very important sensory system. Many behavioral deficits have been reported by other authors after rat vibrissal afferent blockades. In the present work we found significant threshold increments to footshock following either reversible nerve block (procaine or nerve pressure) or section of the vibrissal afferent nerves, but not following vibrissae trimming.
View Article and Find Full Text PDFBlockage of vibrissae afferents: I. Motor effects.
Arch Ital Biol
February 2004
Cátedra de Neurociencia, Facultad de Medicina, Universidad Nacional de Tucumán, Dpto. Fisiología y Neurociencia, INSIBIO, CONICET, Tucumán, Argentina.
In the past, it has been proposed that the rat vibrissae play an important role in other hand, postural abnormalities, muscle tone decreases and hypomotility after sensory organ destructions were proposed as evidence supporting the "level setting" or "tonic" hypothesis. This hypothesis postulates that afferent activity, besides its well know transductive functions, sets the excitability state of the central nervous system. We thought the vibrissal system to be a good model to dissect these two postulated roles because vibrissae trimming would annul the transductive function without affecting the integrity of nerve activity.
View Article and Find Full Text PDFDevelopment of parasagittal zonation in the rat cerebellar cortex: MabQ113 antigenic bands are created postnatally by the suppression of antigen expression in a subset of Purkinje cells.
J Comp Neurol
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Department of Biochemistry, Faculty of Medicine, Laval University, Quebec, Canada.
Monoclonal antibody mabQ113 recognizes a polypeptide antigen that, in the adult cerebellum, is confined to a subset of Purkinje cells that are clustered together to form parasagittal bands interposed by similar nonimmunoreactive bands. The Purkinje cell compartments are congruent with bands of climbing fibers projecting from subregions of the inferior olivary complex (IOC). The array of mabQ113 parasagittal bands appears late in the development of the cortex.
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